Squidoo, a huge user generated content web site founded by Seth Godin, announced they are now nofollowing all outbound links.

I am surprised it took so long. It was founded in 2005 and has been used by SEOs for years for getting links or content into Google. I believe Squidoo was hit hard after Panda.

That being said, Squidoo said:

In 2010, Squidoo had 1.5 million hand-built “lenses” or pages.

There is forum reaction from SEOs at a couple forums including SEOmoz and Warrior Forums, here is one comment:

Forum discussion at SEOmoz and Warrior Forums.